Inhibitory action of orotate, 2-thioorotate and isoorotate on nucleotide metabolism and nucleic acid synthesis in hepatoma cells.

Lea, M A

Inhibitory action of orotate, 2-thioorotate and isoorotate on nucleotide metabolism and nucleic acid synthesis in hepatoma cells. [electronic resource] - The International journal of biochemistry Sep 1992 - 1453-9 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0020-711X

10.1016/0020-711x(92)90071-8 doi


Animals
Carcinoma, Hepatocellular--metabolism
Cell Line
DNA, Neoplasm--biosynthesis
Humans
Liver Neoplasms--metabolism
Nucleotides--metabolism
Orotic Acid--analogs & derivatives
Rats
Rats, Sprague-Dawley
Tumor Cells, Cultured