Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation.

Frattali, A L

Transmembrane signaling by the human insulin receptor kinase. Relationship between intramolecular beta subunit trans- and cis-autophosphorylation and substrate kinase activation. [electronic resource] - The Journal of biological chemistry Sep 1992 - 19521-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0021-9258


Base Sequence
Enzyme Activation
HeLa Cells
Humans
Insulin--pharmacology
Macromolecular Substances
Molecular Sequence Data
Mutagenesis, Site-Directed
Oligodeoxyribonucleotides--chemistry
Phosphorylation
Protein-Tyrosine Kinases--metabolism
Receptor, Insulin--metabolism
Recombinant Proteins
Signal Transduction
Structure-Activity Relationship