Design of a functional hexapeptide antagonist of endothelin.

Cody, W L

Design of a functional hexapeptide antagonist of endothelin. [electronic resource] - Journal of medicinal chemistry Aug 1992 - 3301-3 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm00095a029 doi


Amino Acid Sequence
Animals
Arachidonic Acid--metabolism
Endothelins--antagonists & inhibitors
Fibroblasts--drug effects
Inositol Phosphates--metabolism
Molecular Sequence Data
Muscle, Smooth, Vascular--drug effects
Oligopeptides--chemistry
Peptide Fragments--chemistry
Rabbits
Rats
Receptors, Cell Surface--metabolism
Receptors, Endothelin
Structure-Activity Relationship
Vasoconstriction--drug effects