Synthesis of 1-methyl-3-phenylpyrazolo[4,3-b]pyridines via a methylation of 4-phthalimino-3-phenylpyrazoles and optimization toward highly potent corticotropin-releasing factor type-1 antagonists.

Huang, Charles Q

Synthesis of 1-methyl-3-phenylpyrazolo[4,3-b]pyridines via a methylation of 4-phthalimino-3-phenylpyrazoles and optimization toward highly potent corticotropin-releasing factor type-1 antagonists. [electronic resource] - Bioorganic & medicinal chemistry letters Oct 2003 - 3371-4 p. digital

Publication Type: Journal Article

0960-894X

10.1016/s0960-894x(03)00622-x doi


Humans
Phthalimides--chemical synthesis
Pyrazoles--chemical synthesis
Pyridines--chemical synthesis
Receptors, Corticotropin-Releasing Hormone--antagonists & inhibitors
Structure-Activity Relationship
CRF Receptor, Type 1