Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization.

Oliynyk, Markiyan

Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization. [electronic resource] - Molecular microbiology Sep 2003 - 1179-90 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0950-382X

10.1046/j.1365-2958.2003.03571.x doi


Base Sequence
Cyclization
DNA, Bacterial--chemistry
Drug Resistance, Bacterial--genetics
Epoxide Hydrolases--genetics
Fatty Acid Synthases--genetics
Gene Deletion
Gene Expression Regulation, Bacterial
Gene Order
Genes, Bacterial
Genes, Regulator
Methyltransferases--genetics
Mixed Function Oxygenases--genetics
Molecular Sequence Data
Monensin--analogs & derivatives
Multienzyme Complexes--genetics
Oxidation-Reduction
Oxidoreductases--genetics
Steroid Isomerases--genetics
Streptomyces--enzymology
Thiolester Hydrolases--genetics