Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes.
Papeleu, Peggy
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. [electronic resource] - Journal of hepatology Sep 2003 - 374-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0168-8278
10.1016/s0168-8278(03)00288-5 doi
Animals
Apoptosis--drug effects
CDC2 Protein Kinase--antagonists & inhibitors
Cell Cycle--drug effects
Cells, Cultured
Cyclin D1--antagonists & inhibitors
DNA--antagonists & inhibitors
DNA Replication--drug effects
Enzyme Inhibitors--pharmacology
Epidermal Growth Factor--pharmacology
G1 Phase--drug effects
Hepatocytes--cytology
Hydroxamic Acids--pharmacology
Male
Mitogens--pharmacology
Protein Synthesis Inhibitors--pharmacology
Proto-Oncogene Proteins c-jun--antagonists & inhibitors
Rats
Rats, Sprague-Dawley
S Phase--drug effects
Trichostatin A induces differential cell cycle arrests but does not induce apoptosis in primary cultures of mitogen-stimulated rat hepatocytes. [electronic resource] - Journal of hepatology Sep 2003 - 374-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0168-8278
10.1016/s0168-8278(03)00288-5 doi
Animals
Apoptosis--drug effects
CDC2 Protein Kinase--antagonists & inhibitors
Cell Cycle--drug effects
Cells, Cultured
Cyclin D1--antagonists & inhibitors
DNA--antagonists & inhibitors
DNA Replication--drug effects
Enzyme Inhibitors--pharmacology
Epidermal Growth Factor--pharmacology
G1 Phase--drug effects
Hepatocytes--cytology
Hydroxamic Acids--pharmacology
Male
Mitogens--pharmacology
Protein Synthesis Inhibitors--pharmacology
Proto-Oncogene Proteins c-jun--antagonists & inhibitors
Rats
Rats, Sprague-Dawley
S Phase--drug effects