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Endothelin B receptor deficiency predisposes to pulmonary edema formation via increased lung vascular endothelial cell growth factor expression.

Carpenter, Todd

Endothelin B receptor deficiency predisposes to pulmonary edema formation via increased lung vascular endothelial cell growth factor expression. [electronic resource] - Circulation research Sep 2003 - 456-63 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

ISSN: 1524-4571

Standard No.: 10.1161/01.RES.0000090994.15442.42 doi

Subjects--Topical Terms:
Animals
Animals, Genetically Modified
Blotting, Western
Capillary Permeability--drug effects
Disease Susceptibility
Endothelial Growth Factors--biosynthesis
Endothelin Receptor Antagonists
Endothelins--metabolism
Hypoxia
Hypoxia-Inducible Factor 1, alpha Subunit
Intercellular Signaling Peptides and Proteins--biosynthesis
Isoxazoles--pharmacology
Lung--blood supply
Lymphokines--biosynthesis
Pulmonary Edema--metabolism
Rats
Rats, Mutant Strains
Receptor, Endothelin A
Receptor, Endothelin B
Receptors, Endothelin--deficiency
Thiophenes--pharmacology
Transcription Factors--metabolism
Vascular Endothelial Growth Factor A
Vascular Endothelial Growth Factors