SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile.

Claustre, Yves

SSR181507, a dopamine D(2) receptor antagonist and 5-HT(1A) receptor agonist. I: Neurochemical and electrophysiological profile. [electronic resource] - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Dec 2003 - 2064-76 p. digital

Publication Type: Comparative Study; Journal Article

0893-133X

10.1038/sj.npp.1300262 doi


5-Hydroxytryptophan--metabolism
Action Potentials--drug effects
Animals
Antipsychotic Agents--pharmacology
Behavior, Animal--drug effects
Binding Sites
Brain--anatomy & histology
Cell Count
Dioxanes--pharmacology
Dopamine--metabolism
Dopamine Antagonists--pharmacology
Dopamine D2 Receptor Antagonists
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Interactions
Electric Stimulation
Electrochemistry--methods
Guanosine 5'-O-(3-Thiotriphosphate)--pharmacokinetics
Haloperidol--pharmacology
Humans
Immunohistochemistry--methods
In Vitro Techniques
Levodopa--metabolism
Male
Microdialysis--methods
Neurons--drug effects
Piperazines--pharmacology
Proto-Oncogene Proteins c-fos--metabolism
Pyridines--pharmacology
Radioligand Assay
Rats
Rats, Sprague-Dawley
Receptor, Serotonin, 5-HT1A--chemistry
Receptors, Dopamine D2--chemistry
Serotonin 5-HT1 Receptor Antagonists
Serotonin Antagonists--pharmacology
Sulfur Isotopes--pharmacokinetics
Time Factors
Tropanes--pharmacology