Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge.

Segal, David S

Escalating dose methamphetamine pretreatment alters the behavioral and neurochemical profiles associated with exposure to a high-dose methamphetamine binge. [electronic resource] - Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology Oct 2003 - 1730-40 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

0893-133X

10.1038/sj.npp.1300247 doi


3,4-Dihydroxyphenylacetic Acid--analysis
Animals
Behavior, Animal--drug effects
Binding Sites
Body Temperature--drug effects
Brain Chemistry--drug effects
Central Nervous System Stimulants--pharmacology
Cocaine--analogs & derivatives
Dopamine--analysis
Dopamine Uptake Inhibitors--pharmacokinetics
Dose-Response Relationship, Drug
Drug Administration Schedule--veterinary
Homovanillic Acid--analysis
Male
Methamphetamine--pharmacology
Motor Activity--drug effects
Neostriatum--anatomy & histology
Rats
Rats, Sprague-Dawley
Stereotyped Behavior--drug effects
Tetrabenazine--analogs & derivatives
Time Factors
Tritium--pharmacokinetics