The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine.

Yamaura, Katsunori

The histamine H2-receptor antagonist, cimetidine, inhibits the articular osteopenia in rats with adjuvant-induced arthritis by suppressing the osteoclast differentiation induced by histamine. [electronic resource] - Journal of pharmacological sciences May 2003 - 43-9 p. digital

Publication Type: Comparative Study; Journal Article

1347-8613

10.1254/jphs.92.43 doi


Animals
Arthritis, Experimental--drug therapy
Bone Density--drug effects
Bone Resorption--drug therapy
Cartilage, Articular--drug effects
Cell Differentiation--drug effects
Cimetidine--pharmacology
Dimaprit--pharmacology
Female
Histamine--pharmacology
Histamine Agonists--pharmacology
Histamine H1 Antagonists--pharmacology
Histamine H2 Antagonists--pharmacology
Osteoclasts--drug effects
Pyrilamine--pharmacology
Rats
Rats, Inbred Lew