Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2.

Goncalves, Isaac

Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2. [electronic resource] - The Journal of biological chemistry Sep 2003 - 34812-22 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M306504200 doi


Animals
Apyrase--pharmacology
Aspirin--pharmacology
Blood Platelets--physiology
Calcium Signaling--drug effects
Fibrinogen--physiology
Humans
Kinetics
Mice
Mice, Knockout
Phospholipase C gamma
Platelet Adhesiveness--physiology
Platelet Aggregation Inhibitors--pharmacology
Platelet Glycoprotein GPIIb-IIIa Complex--drug effects
Type C Phospholipases--blood