FK506 restores sensitivity of thymic lymphomas to calcium-mediated apoptosis and the inducible expression of Fas ligand.

Kalas, Wojciech

FK506 restores sensitivity of thymic lymphomas to calcium-mediated apoptosis and the inducible expression of Fas ligand. [electronic resource] - Anticancer research - 1613-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0250-7005


Animals
Apoptosis--drug effects
Calcineurin Inhibitors
Calcium Signaling--drug effects
DNA-Binding Proteins--biosynthesis
Drug Resistance, Neoplasm
Enzyme Inhibitors--pharmacology
Etoposide--pharmacology
Fas Ligand Protein
Gene Expression Regulation, Neoplastic--drug effects
Ionomycin--pharmacology
Ionophores--pharmacology
Isoquinolines--pharmacology
Lymphoma--pathology
Membrane Glycoproteins--biosynthesis
Mice
Mice, Transgenic
Neoplasm Proteins--biosynthesis
Nuclear Receptor Subfamily 4, Group A, Member 1
Protein Serine-Threonine Kinases--antagonists & inhibitors
Receptors, Cytoplasmic and Nuclear
Receptors, Steroid
Sulfonamides
Tacrolimus--pharmacology
Thymus Neoplasms--pathology
Transcription Factors--biosynthesis
Tumor Cells, Cultured--drug effects
fas Receptor--biosynthesis