The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain.

Radziwill, G

The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain. [electronic resource] - Molecular and cellular biology Jul 2003 - 4663-72 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0270-7306

10.1128/MCB.23.13.4663-4672.2003 doi


Amino Acid Sequence
Binding Sites
Cell Division
Cell Line
Down-Regulation
Enzyme Activation
Glutathione Transferase--metabolism
Humans
Immunoblotting
Kinesins--metabolism
Ligands
Microscopy, Fluorescence
Mitogen-Activated Protein Kinases--metabolism
Models, Biological
Models, Genetic
Molecular Sequence Data
Myosins--metabolism
Oncogene Proteins--metabolism
Phosphorylation
Plasmids--metabolism
Precipitin Tests
Protein Binding
Protein Structure, Tertiary
Protein-Tyrosine Kinases
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-bcr
Recombinant Fusion Proteins--metabolism
Sequence Homology, Amino Acid
Signal Transduction
Transfection
ras Proteins--metabolism