Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis.

Schmidt, Jens

Drug targeting by long-circulating liposomal glucocorticosteroids increases therapeutic efficacy in a model of multiple sclerosis. [electronic resource] - Brain : a journal of neurology Aug 2003 - 1895-904 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-8950

10.1093/brain/awg176 doi


Animals
Apoptosis--drug effects
Brain--metabolism
Disease Models, Animal
Encephalomyelitis, Autoimmune, Experimental--drug therapy
Female
Glucocorticoids--administration & dosage
Liposomes
Multiple Sclerosis--drug therapy
Neuroglia--drug effects
Polyethylene Glycols
Prednisolone--administration & dosage
Rats
Rats, Inbred Lew
Spinal Cord--metabolism
T-Lymphocytes--drug effects
Tissue Distribution