Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist.

Burbridge, Mike F

Decrease in survival threshold of quiescent colon carcinoma cells in the presence of a small molecule integrin antagonist. [electronic resource] - Molecular pharmacology Jun 2003 - 1281-8 p. digital

Publication Type: Journal Article

0026-895X

10.1124/mol.63.6.1281 doi


Apoptosis
Caspase 8
Caspase 9
Caspases--metabolism
Cell Adhesion
Cell Survival--drug effects
Colonic Neoplasms--enzymology
Cycloheptanes--pharmacology
Enzyme Activation
Focal Adhesion Kinase 1
Focal Adhesion Protein-Tyrosine Kinases
HT29 Cells
Humans
Integrin alpha5--drug effects
Integrins--antagonists & inhibitors
Membrane Proteins--chemistry
Mitogen-Activated Protein Kinases--metabolism
Phosphorylation
Protein Structure, Tertiary
Protein-Tyrosine Kinases--metabolism
Pyridines--pharmacology
bcl-2 Homologous Antagonist-Killer Protein