Differentiating pathogenic mutations from polymorphic alterations in the splice sites of BRCA1 and BRCA2.

Claes, Kathleen

Differentiating pathogenic mutations from polymorphic alterations in the splice sites of BRCA1 and BRCA2. [electronic resource] - Genes, chromosomes & cancer Jul 2003 - 314-20 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1045-2257

10.1002/gcc.10221 doi


Adult
Age of Onset
Aged
Aged, 80 and over
Breast Neoplasms--genetics
Breast Neoplasms, Male--genetics
Cell Line, Transformed
Female
Frameshift Mutation--genetics
Genes, BRCA1
Genes, BRCA2
Genetic Predisposition to Disease--genetics
Humans
Male
Middle Aged
Mutation
Ovarian Neoplasms--genetics
Polymorphism, Genetic--genetics
RNA Splice Sites--genetics
Reading Frames--genetics