Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression.
Perloff, M D
Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Apr 2003 - 365-77 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0049-8254
10.1080/0049825031000066259 doi
Algorithms
Animals
Anti-Anxiety Agents--metabolism
Antibodies, Blocking--pharmacology
Biotransformation
Blotting, Western
Chromatography, High Pressure Liquid
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Inhibitors--pharmacology
In Vitro Techniques
Intestinal Mucosa--metabolism
Isoenzymes--antagonists & inhibitors
Ketoconazole--pharmacology
Kinetics
Mice
Mice, Inbred ICR
Microsomes--metabolism
Microsomes, Liver--enzymology
Midazolam--metabolism
Organ Specificity
Ritonavir--pharmacology
Troleandomycin--pharmacology
Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression. [electronic resource] - Xenobiotica; the fate of foreign compounds in biological systems Apr 2003 - 365-77 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
0049-8254
10.1080/0049825031000066259 doi
Algorithms
Animals
Anti-Anxiety Agents--metabolism
Antibodies, Blocking--pharmacology
Biotransformation
Blotting, Western
Chromatography, High Pressure Liquid
Cytochrome P-450 Enzyme Inhibitors
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Inhibitors--pharmacology
In Vitro Techniques
Intestinal Mucosa--metabolism
Isoenzymes--antagonists & inhibitors
Ketoconazole--pharmacology
Kinetics
Mice
Mice, Inbred ICR
Microsomes--metabolism
Microsomes, Liver--enzymology
Midazolam--metabolism
Organ Specificity
Ritonavir--pharmacology
Troleandomycin--pharmacology