The tumor-selective over-expression of the human Hsp70 gene is attributed to the aberrant controls at both initiation and elongation levels of transcription.

Cai, Ling

The tumor-selective over-expression of the human Hsp70 gene is attributed to the aberrant controls at both initiation and elongation levels of transcription. [electronic resource] - Cell research Apr 2003 - 93-109 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1001-0602

10.1038/sj.cr.7290154 doi


5' Untranslated Regions--genetics
Base Sequence--genetics
Cell Transformation, Neoplastic--genetics
Gene Expression Regulation, Neoplastic--genetics
Genes, Regulator--genetics
HSP70 Heat-Shock Proteins--biosynthesis
Humans
Mutation--genetics
Neoplasms--genetics
Promoter Regions, Genetic--genetics
Protein Biosynthesis--genetics
RNA, Messenger--biosynthesis
Transcription Initiation Site--physiology
Transcriptional Elongation Factors--genetics
Tumor Cells, Cultured
Tumor Suppressor Protein p53--deficiency