5-fluorouracil: mechanisms of action and clinical strategies.

Longley, Daniel B

5-fluorouracil: mechanisms of action and clinical strategies. [electronic resource] - Nature reviews. Cancer May 2003 - 330-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

1474-175X

10.1038/nrc1074 doi


Animals
Antimetabolites, Antineoplastic--pharmacology
Biomarkers
Dihydrouracil Dehydrogenase (NADP)
Fluorouracil--pharmacology
Humans
Interferons--pharmacology
Microsatellite Repeats
Oligonucleotide Array Sequence Analysis
Oxidoreductases--antagonists & inhibitors
RNA--metabolism
Thymidine Phosphorylase--genetics
Thymidylate Synthase--genetics
Tumor Suppressor Protein p53--physiology