Homology modelling of the nuclear receptors: human oestrogen receptorbeta (hERbeta), the human pregnane-X-receptor (PXR), the Ah receptor (AhR) and the constitutive androstane receptor (CAR) ligand binding domains from the human oestrogen receptor alpha (hERalpha) crystal structure, and the human peroxisome proliferator activated receptor alpha (PPARalpha) ligand binding domain from the human PPARgamma crystal structure.

Jacobs, M N

Homology modelling of the nuclear receptors: human oestrogen receptorbeta (hERbeta), the human pregnane-X-receptor (PXR), the Ah receptor (AhR) and the constitutive androstane receptor (CAR) ligand binding domains from the human oestrogen receptor alpha (hERalpha) crystal structure, and the human peroxisome proliferator activated receptor alpha (PPARalpha) ligand binding domain from the human PPARgamma crystal structure. [electronic resource] - The Journal of steroid biochemistry and molecular biology Feb 2003 - 117-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review

0960-0760

10.1016/s0960-0760(03)00021-9 doi


Amino Acid Sequence
Constitutive Androstane Receptor
Crystallography, X-Ray
Estrogen Receptor alpha
Estrogen Receptor beta
Humans
Ligands
Models, Anatomic
Models, Biological
Models, Molecular
Models, Theoretical
Molecular Sequence Data
Protein Binding
Protein Conformation
Protein Structure, Tertiary
Receptors, Aryl Hydrocarbon--chemistry
Receptors, Cytoplasmic and Nuclear--chemistry
Receptors, Estrogen--chemistry
Transcription Factors--chemistry