Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors.

Drexler, H C A

Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors. [electronic resource] - Cell death and differentiation Mar 2003 - 290-301 p. digital

Publication Type: Journal Article

1350-9047

10.1038/sj.cdd.4401159 doi


Antibiotics, Antineoplastic--pharmacology
Aphidicolin--pharmacology
Apoptosis
Blotting, Western
Caspases--metabolism
Cell Cycle
Cell Cycle Proteins--biosynthesis
Cell Division
Cell Nucleus--metabolism
Cell Separation
Cyclin-Dependent Kinase Inhibitor p27
Cysteine Endopeptidases
Cysteine Proteinase Inhibitors--pharmacology
Dose-Response Relationship, Drug
Doxorubicin--pharmacology
Flow Cytometry
Genetic Vectors
Hemoglobins--metabolism
Humans
K562 Cells
Leupeptins--pharmacology
Microscopy, Fluorescence
Models, Genetic
Multienzyme Complexes--antagonists & inhibitors
Oligopeptides--pharmacology
Proteasome Endopeptidase Complex
Retroviridae--genetics
S Phase--drug effects
Time Factors
Transfection
Tumor Suppressor Proteins--biosynthesis