Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies.

Galés, Céline

Identification of tyrosine 189 and asparagine 358 of the cholecystokinin 2 receptor in direct interaction with the crucial C-terminal amide of cholecystokinin by molecular modeling, site-directed mutagenesis, and structure/affinity studies. [electronic resource] - Molecular pharmacology May 2003 - 973-82 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0026-895X

10.1124/mol.63.5.973 doi


Animals
Asparagine--genetics
COS Cells
Cholecystokinin--genetics
Models, Molecular
Mutagenesis, Site-Directed
Protein Structure, Tertiary
Receptor, Cholecystokinin B
Receptors, Cholecystokinin--genetics
Tyrosine--genetics