The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar.

Monnier, Philippe P

The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar. [electronic resource] - Molecular and cellular neurosciences Mar 2003 - 319-30 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1044-7431

10.1016/s1044-7431(02)00035-0 doi


ADP Ribose Transferases--pharmacology
Amides--pharmacology
Animals
Axons--enzymology
Botulinum Toxins--pharmacology
Cells, Cultured
Chick Embryo
Chickens
Chondroitin Sulfate Proteoglycans--pharmacology
Cicatrix--metabolism
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Gene Products, tat--pharmacology
Intracellular Signaling Peptides and Proteins
Nerve Regeneration--drug effects
Neurites--enzymology
Neuroglia--enzymology
Protein Serine-Threonine Kinases--metabolism
Pyridines--pharmacology
Rats
Rats, Inbred Lew
Recombinant Fusion Proteins--pharmacology
Retinal Ganglion Cells--cytology
Spinal Cord Injuries--metabolism
rho GTP-Binding Proteins--metabolism
rho-Associated Kinases