Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration.

Rozenfeld, Claudia

Soluble factors released by Toxoplasma gondii-infected astrocytes down-modulate nitric oxide production by gamma interferon-activated microglia and prevent neuronal degeneration. [electronic resource] - Infection and immunity Apr 2003 - 2047-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0019-9567

10.1128/IAI.71.4.2047-2057.2003 doi


Animals
Astrocytes--immunology
Cells, Cultured
Coculture Techniques
Culture Media, Conditioned--pharmacology
Cyclic AMP--biosynthesis
Dinoprostone--biosynthesis
Down-Regulation--drug effects
Interferon-gamma--immunology
Interleukin-10--metabolism
Mice
Mice, Inbred BALB C
Microglia--drug effects
Neurons--immunology
Nitric Oxide--biosynthesis
Solubility
Toxoplasma--pathogenicity