Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal.

Du, Jun

Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal. [electronic resource] - Journal of cellular biochemistry Apr 2003 - 1235-46 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0730-2312

10.1002/jcb.10478 doi


3T3 Cells
Animals
Cells, Cultured
Cyclin-Dependent Kinase Inhibitor p21
Cyclins--biosynthesis
Diabetes Mellitus--metabolism
Drug Interactions
Enzyme Inhibitors--pharmacology
Growth Inhibitors--pharmacology
Humans
Insulin-Like Growth Factor I--pharmacology
MAP Kinase Kinase Kinase 1
Mice
Mitogen-Activated Protein Kinases--analysis
Protein Serine-Threonine Kinases--analysis
Pyruvaldehyde--pharmacology
Signal Transduction--physiology