Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm.

Wickman, Grant

Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm. [electronic resource] - Circulation research Apr 2003 - 809-16 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1524-4571

10.1161/01.RES.0000066663.12256.B2 doi


1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine--analogs & derivatives
Amides--pharmacology
Animals
Basilar Artery--cytology
Benzamides--pharmacology
Biological Transport--drug effects
Cell Membrane--metabolism
Cells, Cultured
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
In Vitro Techniques
Indoles--pharmacology
Intracellular Signaling Peptides and Proteins
Isoenzymes--metabolism
Muscle, Smooth, Vascular--cytology
Oxyhemoglobins--pharmacology
Protein Kinase C--antagonists & inhibitors
Protein Serine-Threonine Kinases--antagonists & inhibitors
Pyridines--pharmacology
Pyrroles--pharmacology
Rabbits
Signal Transduction--drug effects
Tetradecanoylphorbol Acetate--pharmacology
Vasoconstriction--drug effects
rho GTP-Binding Proteins--metabolism
rho-Associated Kinases