Coordinate down-regulation of cartilage matrix gene expression in Bcl-2 deficient chondrocytes is associated with decreased SOX9 expression and decreased mRNA stability.

Kinkel, Mary D

Coordinate down-regulation of cartilage matrix gene expression in Bcl-2 deficient chondrocytes is associated with decreased SOX9 expression and decreased mRNA stability. [electronic resource] - Journal of cellular biochemistry Apr 2003 - 941-53 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0730-2312

10.1002/jcb.10442 doi


Aggrecans
Animals
Cell Line
Chondrocytes--physiology
Collagen Type II--genetics
Dactinomycin
Down-Regulation
Extracellular Matrix Proteins--analysis
Gene Expression Regulation
Glycoproteins--analysis
High Mobility Group Proteins--genetics
Lectins, C-Type
Matrilin Proteins
Polymerase Chain Reaction--methods
Proteoglycans--genetics
Proto-Oncogene Proteins c-bcl-2--deficiency
RNA Stability
RNA, Messenger--analysis
Rats
SOX9 Transcription Factor
Signal Transduction
Transcription Factors--genetics
Transfection