Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade.

Tuder, Rubin M

Oxidative stress and apoptosis interact and cause emphysema due to vascular endothelial growth factor receptor blockade. [electronic resource] - American journal of respiratory cell and molecular biology Jul 2003 - 88-97 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

1044-1549

10.1165/rcmb.2002-0228OC doi


Angiogenesis Inhibitors--pharmacology
Animals
Apoptosis--drug effects
Aspartic Acid--analogs & derivatives
Biomarkers--analysis
Caspase Inhibitors
Cysteine Proteinase Inhibitors--pharmacology
Indoles--pharmacology
Lung--drug effects
Male
Molecular Mimicry
Oxidative Stress--drug effects
Pulmonary Alveoli--drug effects
Pulmonary Emphysema--chemically induced
Pyrroles--pharmacology
Rats
Rats, Sprague-Dawley
Receptors, Vascular Endothelial Growth Factor--antagonists & inhibitors
Superoxide Dismutase--chemistry