Mast cell-mediated apoptosis of endothelial cells in vitro: a paracrine mechanism involving TNF-alpha-mediated down-regulation of bcl-2 expression.

Lätti, Soili

Mast cell-mediated apoptosis of endothelial cells in vitro: a paracrine mechanism involving TNF-alpha-mediated down-regulation of bcl-2 expression. [electronic resource] - Journal of cellular physiology Apr 2003 - 130-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9541

10.1002/jcp.10235 doi


Animals
Apoptosis--physiology
Cell Degranulation
Cells, Cultured
Coculture Techniques
Cytochrome c Group--metabolism
Cytoplasmic Granules--metabolism
Down-Regulation--physiology
Endothelium, Vascular--cytology
Male
Mast Cells--drug effects
Paracrine Communication--physiology
Proto-Oncogene Proteins--biosynthesis
Proto-Oncogene Proteins c-bcl-2--genetics
RNA, Messenger--metabolism
Rats
Rats, Wistar
Tumor Necrosis Factor-alpha--biosynthesis
bcl-2-Associated X Protein
p-Methoxy-N-methylphenethylamine--pharmacology