Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons.

Holtz, William Andrew

Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. [electronic resource] - The Journal of biological chemistry May 2003 - 19367-77 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M211821200 doi


1-Methyl-4-phenylpyridinium--pharmacology
Blotting, Western
CCAAT-Enhancer-Binding Proteins--genetics
Carrier Proteins--genetics
Caspases--metabolism
Cell Death--drug effects
Cells, Cultured
Cysteine Endopeptidases--metabolism
DNA-Binding Proteins--genetics
Dopamine--analogs & derivatives
Embryo, Mammalian
Embryo, Nonmammalian
Endoplasmic Reticulum--physiology
Endoplasmic Reticulum Chaperone BiP
Eukaryotic Initiation Factor-2--metabolism
Gene Expression Regulation--drug effects
Heat-Shock Proteins
Immunohistochemistry
Mesencephalon
Molecular Chaperones--genetics
Multienzyme Complexes--metabolism
Neurons--drug effects
Oxidopamine--pharmacology
Parkinson Disease, Secondary--chemically induced
Phosphorus Compounds
Proteasome Endopeptidase Complex
Protein Folding
Proto-Oncogene Proteins c-jun--genetics
RNA, Messenger--analysis
Regulatory Factor X Transcription Factors
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factor CHOP
Transcription Factors--genetics
Ubiquitin--metabolism
eIF-2 Kinase--metabolism