Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy.

Patel, Hema J

Activation of peroxisome proliferator-activated receptors in human airway smooth muscle cells has a superior anti-inflammatory profile to corticosteroids: relevance for chronic obstructive pulmonary disease therapy. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2003 - 2663-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0022-1767

10.4049/jimmunol.170.5.2663 doi


Adolescent
Adult
Anti-Inflammatory Agents--pharmacology
Apoptosis--drug effects
Blotting, Western
Cell Division--drug effects
Cells, Cultured
DNA Fragmentation--drug effects
Dexamethasone--pharmacology
Female
Granulocyte Colony-Stimulating Factor--metabolism
Granulocyte-Macrophage Colony-Stimulating Factor--metabolism
Growth Inhibitors--pharmacology
Humans
Interleukin-1--pharmacology
Ligands
Male
Middle Aged
Muscle, Smooth--cytology
Peroxisomes--genetics
Prostaglandin D2--analogs & derivatives
Protein Isoforms--biosynthesis
Pulmonary Disease, Chronic Obstructive--drug therapy
Pyrimidines--metabolism
RNA, Messenger--biosynthesis
Receptors, Cytoplasmic and Nuclear--biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Thiazoles--metabolism
Thiazolidinediones
Trachea--cytology
Transcription Factors--biosynthesis