Genomic characterization of the chromosomal breakpoints of t(4;14) of multiple myeloma suggests more than one possible aetiological mechanism.

Fenton, James A L

Genomic characterization of the chromosomal breakpoints of t(4;14) of multiple myeloma suggests more than one possible aetiological mechanism. [electronic resource] - Oncogene Feb 2003 - 1103-13 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1206335 doi


B-Lymphocytes--pathology
Base Sequence
Cell Transformation, Neoplastic--genetics
Chromosome Breakage
Chromosomes, Human, Pair 14--genetics
Chromosomes, Human, Pair 4--genetics
Clone Cells--pathology
Gene Rearrangement, B-Lymphocyte, Heavy Chain
Genes, Immunoglobulin
Genes, Switch
Humans
Immunoglobulin Class Switching--genetics
Immunoglobulin Switch Region--genetics
Immunoglobulin mu-Chains--genetics
Models, Biological
Molecular Sequence Data
Multiple Myeloma--etiology
Neoplastic Stem Cells--pathology
Polymerase Chain Reaction--methods
Sequence Alignment
Sequence Homology, Nucleic Acid
Translocation, Genetic--genetics