Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn's disease.
Ito, Hiroaki
Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn's disease. [electronic resource] - Journal of gastroenterology Nov 2002 - 56-61 p. digital
Publication Type: Comparative Study; Journal Article
0944-1174
10.1007/BF03326415 doi
Animals
Antibodies, Anti-Idiotypic--pharmacology
Antibodies, Monoclonal--drug effects
Apoptosis--drug effects
Cells, Cultured
Crohn Disease--drug therapy
Cytokines--analysis
Disease Models, Animal
Female
Immunoglobulin G--pharmacology
Immunohistochemistry
In Situ Nick-End Labeling
Intercellular Adhesion Molecule-1--analysis
Intestinal Mucosa--metabolism
Male
Mice
Mice, SCID
Nitric Oxide Synthase--analysis
Probability
Receptors, Interleukin-6--drug effects
Reference Values
Reverse Transcriptase Polymerase Chain Reaction--methods
Sensitivity and Specificity
T-Lymphocytes--drug effects
Vascular Cell Adhesion Molecule-1--analysis
Anti-IL-6 receptor monoclonal antibody inhibits leukocyte recruitment and promotes T-cell apoptosis in a murine model of Crohn's disease. [electronic resource] - Journal of gastroenterology Nov 2002 - 56-61 p. digital
Publication Type: Comparative Study; Journal Article
0944-1174
10.1007/BF03326415 doi
Animals
Antibodies, Anti-Idiotypic--pharmacology
Antibodies, Monoclonal--drug effects
Apoptosis--drug effects
Cells, Cultured
Crohn Disease--drug therapy
Cytokines--analysis
Disease Models, Animal
Female
Immunoglobulin G--pharmacology
Immunohistochemistry
In Situ Nick-End Labeling
Intercellular Adhesion Molecule-1--analysis
Intestinal Mucosa--metabolism
Male
Mice
Mice, SCID
Nitric Oxide Synthase--analysis
Probability
Receptors, Interleukin-6--drug effects
Reference Values
Reverse Transcriptase Polymerase Chain Reaction--methods
Sensitivity and Specificity
T-Lymphocytes--drug effects
Vascular Cell Adhesion Molecule-1--analysis