Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis.

Moshous, Despina

Partial T and B lymphocyte immunodeficiency and predisposition to lymphoma in patients with hypomorphic mutations in Artemis. [electronic resource] - The Journal of clinical investigation Feb 2003 - 381-7 p. digital

Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI16774 doi


Adolescent
B-Lymphocytes--immunology
Blotting, Southern
Child
Child, Preschool
DNA-Binding Proteins
Endonucleases
Family Health
Female
Fibroblasts--metabolism
Flow Cytometry
Genetic Predisposition to Disease
Humans
Immunohistochemistry
Immunologic Deficiency Syndromes--genetics
Infant
Lymphoma--etiology
Lymphoma, B-Cell--genetics
Male
Mutation
Nuclear Proteins
Polymerase Chain Reaction
Severe Combined Immunodeficiency--genetics
T-Lymphocytes--immunology
Time Factors
beta-Lactamases--genetics