A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli.

Cheung, Kevin J

A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli. [electronic resource] - Genome research Feb 2003 - 206-15 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

1088-9051

10.1101/gr.401003 doi


Anti-Bacterial Agents--pharmacology
Bacterial Proteins--genetics
Cytoprotection--drug effects
DNA Gyrase--drug effects
DNA Topoisomerases, Type I--genetics
DNA, Bacterial--genetics
DNA, Superhelical--genetics
Escherichia coli--drug effects
Escherichia coli Proteins--genetics
Gene Expression Profiling--methods
Gene Expression Regulation, Bacterial--drug effects
Genome, Bacterial
Multigene Family--drug effects
Novobiocin--pharmacology
Oligonucleotide Array Sequence Analysis--methods
Osmotic Pressure
Pefloxacin--pharmacology
Potassium--metabolism
Sigma Factor--genetics
Sodium Chloride--pharmacology
Stress, Mechanical
Temperature
Transcription, Genetic--drug effects