Simultaneous determination of nimesulide and hydroxynimesulide in rat plasma, cerebrospinal fluid and brain by liquid chromatography using solid-phase extraction.

Ferrario, Paolo

Simultaneous determination of nimesulide and hydroxynimesulide in rat plasma, cerebrospinal fluid and brain by liquid chromatography using solid-phase extraction. [electronic resource] - Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Mar 2003 - 227-36 p. digital

Publication Type: Journal Article

1570-0232

10.1016/s1570-0232(02)00857-7 doi


Animals
Anti-Inflammatory Agents, Non-Steroidal--analysis
Brain--metabolism
Calibration
Chromatography, Liquid
Linear Models
Male
Rats
Reference Standards
Reproducibility of Results
Spectrophotometry, Ultraviolet
Sulfonamides--analysis