COX-2 inhibition potentiates the antiproteinuric effect of enalapril in uninephrectomized SHR.

Harding, Pamela

COX-2 inhibition potentiates the antiproteinuric effect of enalapril in uninephrectomized SHR. [electronic resource] - Prostaglandins, leukotrienes, and essential fatty acids Jan 2003 - 17-25 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0952-3278

10.1016/s0952-3278(02)00231-4 doi


Angiotensin-Converting Enzyme Inhibitors--pharmacology
Animals
Antihypertensive Agents--pharmacology
Blood Pressure
Body Weight
Collagen Type II--metabolism
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Enalapril--pharmacology
Hypertrophy--pathology
Isoenzymes--antagonists & inhibitors
Kidney Diseases--enzymology
Male
Nephrectomy
Nitrobenzenes--pharmacology
Organ Size
Prostaglandin-Endoperoxide Synthases--physiology
Prostaglandins--urine
Proteinuria--enzymology
Rats
Rats, Inbred SHR
Rats, Inbred WKY
Sulfonamides--pharmacology