Metal ions induce bone-resorbing cytokine production through the redox pathway in synoviocytes and bone marrow macrophages.

Niki, Yasuo

Metal ions induce bone-resorbing cytokine production through the redox pathway in synoviocytes and bone marrow macrophages. [electronic resource] - Biomaterials Apr 2003 - 1447-57 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0142-9612

10.1016/s0142-9612(02)00531-8 doi


Adult
Antioxidants--pharmacology
Bone Marrow Cells--drug effects
Bone Resorption--chemically induced
Cytokines--biosynthesis
DNA--metabolism
Female
Humans
In Vitro Techniques
Interleukin-1--biosynthesis
Interleukin-6--biosynthesis
Joint Prosthesis--adverse effects
Macrophages--drug effects
Male
Materials Testing
Metals--toxicity
Middle Aged
NF-kappa B--metabolism
Oxidation-Reduction
Proline--analogs & derivatives
Prosthesis Failure
Reactive Oxygen Species--metabolism
Synovial Membrane--drug effects
Thiocarbamates--pharmacology
Tumor Necrosis Factor-alpha--biosynthesis