Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7.

Tajima, Yoshitaka

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7. [electronic resource] - The Journal of biological chemistry Mar 2003 - 10716-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M212663200 doi


Active Transport, Cell Nucleus--physiology
Amino Acid Sequence
Animals
COS Cells
DNA-Binding Proteins--chemistry
HeLa Cells
Humans
Karyopherins--physiology
Ligases--metabolism
Molecular Sequence Data
Protein Transport
Receptors, Cytoplasmic and Nuclear
Smad7 Protein
Trans-Activators--chemistry
Transcription, Genetic
Transforming Growth Factor beta--physiology
Ubiquitin-Protein Ligases
Exportin 1 Protein