Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes.

Hiyoshi, Hironobu

Squalene synthase inhibitors suppress triglyceride biosynthesis through the farnesol pathway in rat hepatocytes. [electronic resource] - Journal of lipid research Jan 2003 - 128-35 p. digital

Publication Type: Journal Article

0022-2275

10.1194/jlr.m200316-jlr200 doi


Animals
Atorvastatin
Benzylamines--pharmacology
Cells, Cultured
Cholesterol--biosynthesis
Enzyme Inhibitors--pharmacology
Farnesol--analogs & derivatives
Farnesyl-Diphosphate Farnesyltransferase--antagonists & inhibitors
Hepatocytes--drug effects
Heptanoic Acids--pharmacology
Lipid Metabolism
Male
Oxidation-Reduction
Pyrroles--pharmacology
Rats
Rats, Sprague-Dawley
Thiophenes--pharmacology
Triglycerides--biosynthesis