Natural history of alkaptonuria.

Phornphutkul, Chanika

Natural history of alkaptonuria. [electronic resource] - The New England journal of medicine Dec 2002 - 2111-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1533-4406

10.1056/NEJMoa021736 doi


4-Hydroxyphenylpyruvate Dioxygenase--antagonists & inhibitors
Adolescent
Adult
Age of Onset
Aged
Aged, 80 and over
Alkaptonuria--classification
Child
Child, Preschool
Connective Tissue Diseases--etiology
Cyclohexanones--therapeutic use
DNA Mutational Analysis
Dioxygenases
Disease Progression
Enzyme Inhibitors--therapeutic use
Female
Heart Valve Diseases--etiology
Homogentisate 1,2-Dioxygenase
Humans
Joint Diseases--etiology
Kidney Calculi--etiology
Life Tables
Linear Models
Longitudinal Studies
Male
Middle Aged
Mutation
Nitrobenzoates--therapeutic use
Oxygenases--genetics
Severity of Illness Index
Tyrosine--metabolism