Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes.

Huh, Yun-Hyun

Differentiation status-dependent regulation of cyclooxygenase-2 expression and prostaglandin E2 production by epidermal growth factor via mitogen-activated protein kinase in articular chondrocytes. [electronic resource] - The Journal of biological chemistry Mar 2003 - 9691-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M211360200 doi


Animals
Cartilage--metabolism
Cell Differentiation
Cell Division
Cells, Cultured
Chondrocytes--enzymology
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--pharmacology
Dinoprostone--metabolism
Dose-Response Relationship, Drug
Enzyme Inhibitors--pharmacology
Epidermal Growth Factor--metabolism
Gene Expression Regulation, Enzymologic
Immunoblotting
Immunohistochemistry
Indomethacin--pharmacology
Isoenzymes--biosynthesis
MAP Kinase Signaling System
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3
Mitogen-Activated Protein Kinases--metabolism
Phenotype
Prostaglandin-Endoperoxide Synthases--biosynthesis
Rabbits
Time Factors
p38 Mitogen-Activated Protein Kinases