p53 mediates DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in SH-SY5Y neuroblastoma cells.

Cui, Hongjuan

p53 mediates DNA damaging drug-induced apoptosis through a caspase-9-dependent pathway in SH-SY5Y neuroblastoma cells. [electronic resource] - Molecular cancer therapeutics Jul 2002 - 679-86 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1535-7163


Apoptosis
Caspase 9
Caspases--metabolism
Cell Nucleus--metabolism
Cyclin-Dependent Kinase Inhibitor p21
Cyclins--metabolism
Cytochrome c Group--metabolism
DNA Damage
DNA Fragmentation
Dose-Response Relationship, Drug
Doxorubicin--pharmacology
Enzyme Activation
Etoposide--pharmacology
Genes, p53
Humans
Immunoblotting
Microscopy, Fluorescence
Mitochondria--enzymology
Neuroblastoma--metabolism
Signal Transduction
Time Factors
Transcription, Genetic
Tumor Cells, Cultured
Tumor Suppressor Protein p53--metabolism