Structural implications of placing cationic residues at either the NH2- or COOH-terminus in a pore-forming synthetic peptide.

Broughman, J R

Structural implications of placing cationic residues at either the NH2- or COOH-terminus in a pore-forming synthetic peptide. [electronic resource] - The Journal of membrane biology Nov 2002 - 93-103 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-2631

10.1007/s00232-002-1027-3 doi


Animals
Cations--chemistry
Cells, Cultured
Chloride Channels--chemistry
Computer Simulation
Dogs
Kidney--physiology
Membrane Potentials--physiology
Models, Molecular
Nuclear Magnetic Resonance, Biomolecular--methods
Peptide Fragments--chemistry
Protein Conformation
Protein Engineering--methods
Protein Structure, Secondary
Receptors, Glycine--chemistry
Sensitivity and Specificity
Structure-Activity Relationship