Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation.

Carlyon, Jason A

Repression of rac2 mRNA expression by Anaplasma phagocytophila is essential to the inhibition of superoxide production and bacterial proliferation. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Dec 2002 - 7009-18 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.169.12.7009 doi


Anaplasma phagocytophilum--cytology
Cell Division--genetics
Down-Regulation--physiology
Ehrlichiosis--metabolism
Gene Expression Profiling
HL-60 Cells--drug effects
Humans
Membrane Glycoproteins--biosynthesis
NADPH Oxidase 2
NADPH Oxidases
Neutrophils--drug effects
RNA, Messenger--analysis
Superoxides--antagonists & inhibitors
Transfection
Tretinoin--pharmacology
rac GTP-Binding Proteins--antagonists & inhibitors
rac1 GTP-Binding Protein--genetics
RAC2 GTP-Binding Protein