Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells.

Bapiro, Tashinga E

Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells. [electronic resource] - European journal of clinical pharmacology Nov 2002 - 537-42 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0031-6970

10.1007/s00228-002-0512-z doi


Albendazole--pharmacology
Antiparasitic Agents--pharmacology
Cell Survival--drug effects
Cytochrome P-450 CYP1A1--biosynthesis
Cytochrome P-450 CYP1A2--biosynthesis
Dose-Response Relationship, Drug
Enzyme Induction
Humans
Polychlorinated Dibenzodioxins--metabolism
Primaquine--pharmacology
Quinine--pharmacology
RNA, Messenger--biosynthesis
Tumor Cells, Cultured