The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors.

Horng, Tiffany

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors. [electronic resource] - Nature Nov 2002 - 329-33 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0028-0836

10.1038/nature01180 doi


Adaptor Proteins, Signal Transducing
Animals
Antigens, Differentiation--genetics
Cell Differentiation--drug effects
Cell Division--drug effects
Cells, Cultured
Cytokines--biosynthesis
Dendritic Cells--cytology
Drosophila Proteins
Female
Immunity, Innate
Interleukin-1--pharmacology
Interleukin-18--pharmacology
Lipopolysaccharides--pharmacology
Macrophages--drug effects
Male
Membrane Glycoproteins--metabolism
Mice
Mice, Inbred C57BL
Mice, Knockout
Mitogen-Activated Protein Kinases--metabolism
Myeloid Differentiation Factor 88
NF-kappa B--metabolism
Receptors, Cell Surface--metabolism
Receptors, Immunologic--genetics
Receptors, Interleukin-1--deficiency
Signal Transduction--drug effects
Spleen--cytology
Substrate Specificity
Toll-Like Receptor 1
Toll-Like Receptor 2
Toll-Like Receptor 4
Toll-Like Receptor 5
Toll-Like Receptor 7
Toll-Like Receptors