Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis.
Mitchell, W Beau
Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. [electronic resource] - Blood Mar 2003 - 2268-76 p. digital
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
10.1182/blood-2002-07-2266 doi
Binding Sites
Calcium--metabolism
Cell Line
Child
Gene Expression
Humans
Immunoblotting
Infant
Isoleucine
Male
Models, Molecular
Mutagenesis
Mutation
Platelet Glycoprotein GPIIb-IIIa Complex--biosynthesis
Platelet Membrane Glycoprotein IIb--chemistry
Static Electricity
Structure-Activity Relationship
Thrombasthenia--genetics
Transfection
Valine
Two novel mutations in the alpha IIb calcium-binding domains identify hydrophobic regions essential for alpha IIbbeta 3 biogenesis. [electronic resource] - Blood Mar 2003 - 2268-76 p. digital
Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0006-4971
10.1182/blood-2002-07-2266 doi
Binding Sites
Calcium--metabolism
Cell Line
Child
Gene Expression
Humans
Immunoblotting
Infant
Isoleucine
Male
Models, Molecular
Mutagenesis
Mutation
Platelet Glycoprotein GPIIb-IIIa Complex--biosynthesis
Platelet Membrane Glycoprotein IIb--chemistry
Static Electricity
Structure-Activity Relationship
Thrombasthenia--genetics
Transfection
Valine