The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo.

Harmala, Lisa A E

The adjuvant effects of Mycobacterium tuberculosis heat shock protein 70 result from the rapid and prolonged activation of antigen-specific CD8+ T cells in vivo. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Nov 2002 - 5622-9 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.169.10.5622 doi


Adjuvants, Immunologic--administration & dosage
Adoptive Transfer
Animals
Antigens, Differentiation--biosynthesis
Bacterial Proteins
CD4-Positive T-Lymphocytes--immunology
CD8-Positive T-Lymphocytes--immunology
Cell Division--genetics
Cell Line--transplantation
Cells, Cultured
Cytotoxicity Tests, Immunologic
Egg Proteins--administration & dosage
Epitopes, T-Lymphocyte--administration & dosage
Freund's Adjuvant--administration & dosage
Genetic Vectors--administration & dosage
HSP70 Heat-Shock Proteins--administration & dosage
Lipopolysaccharides--analysis
Lymphocyte Activation--genetics
Lymphocyte Count
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mycobacterium tuberculosis--genetics
Ovalbumin--administration & dosage
Peptide Fragments
Recombinant Fusion Proteins--administration & dosage
T-Lymphocytes, Cytotoxic--immunology
Tumor Cells, Cultured