Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.

Pene, Frédéric

Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma. [electronic resource] - Oncogene Sep 2002 - 6587-97 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0950-9232

10.1038/sj.onc.1205923 doi


Apoptosis
Caspases--physiology
Cell Cycle
Cell Cycle Proteins--analysis
Cell Division
Cell Line
Cyclin D1--analysis
Fas Ligand Protein
Humans
Interleukin-6--biosynthesis
Membrane Glycoproteins--physiology
Microfilament Proteins--biosynthesis
Mitogen-Activated Protein Kinases--physiology
Multiple Myeloma--pathology
Muscle Proteins
PTEN Phosphohydrolase
Phosphatidylinositol 3-Kinases--physiology
Phosphoric Monoester Hydrolases--analysis
Protein Kinases--physiology
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins--physiology
Proto-Oncogene Proteins c-akt
Ribosomal Protein S6 Kinases--physiology
S-Phase Kinase-Associated Proteins
TOR Serine-Threonine Kinases
Tumor Suppressor Proteins--analysis
fas Receptor--physiology